Our Published Research

Our progress in architecting the computational substrate for science (3 papers currently in review).

Published Papers

Present lab member at time of publicationNon lab member at time of publication

Downregulation of KRT proteins in the Neuroendocrine System of Amyotrophic Lateral Sclerosis with PT150 as a Multi Target Neuroprotectant

Samarth DunakheArnav SharmaAryav Das

International Science and Engineering Fair 2025 + bioRxiv

Investigated the role of KRT proteins in ALS neuroendocrine dysfunction and PT150's neuroprotective effects.

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Published: 2025-03-18

TEMPiRL: Foundational Compounding Temporal Drift Theory for Temporal Graph Adaptation in Large Language Models

Arnav SharmaKarthik Srikumar

Continual and Compatible Foundation Models @ NeurIPS 2025

An additive architecture for temporal-graph adaptation in Large Language Models, enhancing their reasoning over time.

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Accepted: 2025-09-23

On the Relationship Between Neural Tangent Kernel Frobenius Distance and Distillation Sample Complexity

Arnav SharmaAhmed WezKarthik Srikumar

Lock-LLM at Neural Information Processing Systems (NeurIPS)

Investigates the theoretical relationship between the Frobenius distance of Neural Tangent Kernels and the sample complexity required for effective model distillation.

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Accepted: 2025-10-02

Patents

Method for Treating ALS Using PT150...

63/811,618 · Filed May 25, 2025

A novel therapeutic method for slowing ALS progression.

Awards

ISEF 1st Place in Comp. Biology

Society for Science, 2025

Not an organizational award, but an award for our research on ALS, split $6,000 amongst 3 people, including our CEO.

Collaborators

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UCSC

Artificial Intelligence Explainability Accountability Lab

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UIUC

Mobility & Fall Prevention Research Lab

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Yee Collins Research Group

Their full group